Chloroprocaine-bupivacaine sequence for obstetric extradural analgesia

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Effect of extradural analgesia using bupivacaine and 2-chloroprocaine on intervillous blood flow during normal labour.

The effect of lumbar extradural analgesia on intervillous blood flow (IBF) during labour was studied in 26 healthy parturients using an i.v. bolus injection of xenon-133. There was a 19% decrease (n.s.) in mean IBF in six parturients (non-extradural control group). Mean IBF increased by 37.5% when 0.25% bupivacaine 10 ml was used and by 35.2% when 2% 2-chloroprocaine 10 ml was used (n.s.). When...

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Bupivacaine toxicity in association with extradural analgesia for caesarean section.

Evidence of central nervous system toxicity was noted in two patients undergoing extradural analgesia for Caesarean section. There was no cardiovascular depression and both patients recovered rapidly. The patients had received total doses of bupivacaine plain solution of 357.5 mg and 356.25 mg, respectively and the relationship of these to the clinical signs of bupivacaine toxicity is discussed.

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Ropivacaine and bupivacaine in obstetric analgesia.

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ژورنال

عنوان ژورنال: Canadian Anaesthetists’ Society Journal

سال: 1975

ISSN: 0008-2856,1496-8975

DOI: 10.1007/bf03004821